Prachi was born in Surat, Gujarat. She learnt in St Joseph Convent, Panchgani and finished her schooling till ninth level in Surat. After that that, she went to Pune for top studies. She learnt at Sinhagad College, Kondhwa, Pune. She began her life history with a little modeling workshop. She was in Pune for higher works and had about completed her junior college when her images were sent to Balaji Telefilms who called her for hearing.
She was 17 when she went away her studies and began her employment with Kasamh Se. Prachi starred in the nonparallel Kasamh Se on Zee TV from where got her renown. She left behind Kasamh Se on 15 April 2008 and was put back by Gurdeep Kohli, after that being fired and drowned in episode 562. Kasamh Se stopped 12 March 2009. In the final episode, Prachi Desai got a extra appearance as the early Bani. She as well did a two day cameo in Kasautii Zindagii Kay, which was publicised on Star Plus. She acted a school student in Prerna’s scho.
Prachi is also joined Jhalak Dikhhla Jaa on 7 September 2007, the America’s dancing show about Indian version. In that show her choreographer is the well known Deepak Singh, And won the first place on that show. Then she came on bollywoods movies and got the much fame. Prachi desai bikini in i me aur main has become very famous in all around the industry.